Russell Wilson threw two touchdown passes and ran for another score as the Seattle Seahawks stifled Philadelphia’s high-powered offence in a 24-14 victory over the Eagles on Sunday.
Wilson had 263 yards passing and ran for 48 to help the Seahawks (9-4) win their third straight.
The defending Super Bowl champions have victories over NFC West-leading Arizona (10-3), San Francisco (7-6) and Philadelphia (9-4) in the last three weeks.
The Eagles host Dallas (9-4) with first place in the NFC East at stake next week.
Tom Brady threw a 69-yard touchdown pass to Julian Edelman midway through the fourth quarter, as the New England Patriots (10-3) beat the San Diego Chargers 23-14 for their eighth win in nine games.
The Patriots clinched their 12th straight 10-win season for the second-longest such streak in NFL history.
Brady completed 28 of 44 passes for 317 yards and two touchdowns.
Denver’s C.J. Anderson ran for three touchdowns as the Broncos overcame a rare unsteady outing by Peyton Manning to defeat the Buffalo Bills 24-17.
Manning’s streak of 51 straight games with a touchdown throw – three shy of Drew Brees’ NFL record – ended on a sun-splashed, almost still afternoon in Denver, where the game-time temperature was a balmy 63 degrees.
Despite three turnovers, the Broncos (10-3) won their third straight game since changing from a pass-oriented attack to a run-heavy approach.
In Arizona, Kerwynn Williams rushed for 100 yards two days after being elevated from the Cardinals practice squad in a 17-14 win over the Kansas City Chiefs.
The NFC West-leading Cardinals (10-3) took the lead when Drew Stanton threw a 26-yard touchdown pass to Jaron Brown in the third quarter.
Jamaal Charles scored two first-half touchdowns on a 63-yard run and 18-yard pass from Alex Smith, but the Chiefs (7-6) were shut out in the second half.
The Indianapolis Colts edged the Cleveland Browns 25-24 after Andrew Luck threw a 1-yard touchdown pass to T.Y. Hilton with 32 seconds left, while Pittsburgh’s Ben Roethlisberger threw three touchdown passes, including a 94-yarder to rookie Martavis Bryant in the fourth quarter that was the longest play from scrimmage this season, as the Steelers downed the Cincinnati Bengals 42-21.
In other games, the Baltimore Ravens played more than 17 minutes before picking up a first down, then overcame a 10-point deficit to beat the Miami Dolphins 28-13, the Oakland Raiders defeated the San Francisco 49ers 24-13, the Carolina Panthers trounced the New Orleans Saints 41-10 and the Detroit Lions downed the Tampa Bay Buccaneers 34-17.
The St. Louis Rams have back-to-back shutouts for the first time since 1945 after a 24-0 domination of the Washington Redskins, the Houston Texans beat the Jacksonville Jaguars 27-13, the Minnesota Vikings overgame the New Jets 30-24 in overtime and the New York Jets were 36-7 winners over the Tennessee Titans.